Canton to Des Moines Megabus
The Megabus corridor from Canton to Des Moines covers 639 miles in roughly 13h 12m, with 7 scheduled departures most days. Floor fares start at $33 when booked far in advance.
Route overview
Megabus operates the Canton–Des Moines corridor with 7 scheduled daily departures, primarily routed via Interstate 75 through the Appalachian foothills. Most travelers book this route for a combination of low fare and frequency: even at the high end of the dynamic-pricing curve, it remains substantially cheaper than rail or rideshare for the same trip.
The total scheduled travel time of 13h 12m reflects driving time plus a short curbside boarding window at each end. On this longer corridor, expect one scheduled meal stop of 20 to 30 minutes at a service plaza partway through the trip.
Where the bus stops
Canton departure: Canton Bus Stop on Cleveland Avenue. Canton Ohio is a Megabus stop near the Pro Football Hall of Fame. SARTA local buses serve the stop and downtown Canton.
Des Moines arrival: Des Moines Greyhound Station on Cherry Street. Des Moines's intercity terminal is east of downtown, near the Iowa Events Center. DART buses connect the terminal across the metro.
Schedule and frequency
Megabus runs 7 scheduled departures per day on this corridor. Departure times shift seasonally and at weekends; the table below shows a representative weekday schedule. Always verify current departure times on Megabus before travel.
| Depart Canton | Arrive Des Moines | Service |
|---|---|---|
| 06:30 | 19:42 | Standard |
| 08:15 | 21:27 | Express |
| 11:00 | 00:12 | Standard |
| 14:30 | 03:42 | Standard |
| 17:45 | 06:57 | Express |
| 21:30 | 10:42 | Overnight |
| 23:15 | 12:27 | Overnight |
Fares and how to book cheap
The Canton–Des Moines Megabus fare floor is $33 when booked at the schedule open, typically 60 to 90 days in advance. Fares climb in tiers as seats sell — most travelers booking inside the two-week window pay $58 to $84, with same-day walk-up fares often at or above the typical maximum.
The cheapest departures on this corridor are mid-week (Tuesday and Wednesday), early Saturday morning, and early Sunday morning. Friday afternoon and Sunday evening are the most expensive slots and the first to sell out. Reserved seating runs an extra $5.00 to $8.00 on top of the base fare.
What to expect on board
Megabus uses single-deck or double-deck coaches on this corridor depending on demand. All buses include free onboard Wi-Fi (best-effort), 110V power outlets at every row, reclining leather or vinyl seats, and an onboard restroom. Standard luggage allowance is one personal item under the seat plus one underbus bag up to 50 lb included in the base fare.
Wi-Fi works well for messaging and email but is unreliable for video streaming, particularly in rural sections of the route. Outlets are functional at most rows; bring a 10,000 mAh battery pack as backup. Climate control runs cool — bring a layer regardless of season.
Megabus vs. Greyhound and FlixBus on this route
This corridor is also served by other intercity carriers in varying frequencies. Greyhound typically runs one to three daily departures with fares starting around $132, often using a dedicated terminal rather than the Megabus curbside stop. FlixBus may also serve this corridor with curbside service comparable to Megabus, sometimes at marginally lower fares for last-minute booking thanks to active promo-code campaigns.
For longer trips like this one, Greyhound's older terminal-based model has the advantage of indoor waiting space and ticket counter support, while Megabus's curbside model wins on price and frequency.
Tips for this corridor
- Book at least 30 days in advance for the best fares; 60+ days lands the $33 floor when available.
- Tuesday, Wednesday and Saturday-morning departures are cheapest.
- Arrive at Canton Bus Stop on Cleveland Avenue 15 to 20 minutes before scheduled departure with your ticket QR code and a photo ID.
- Tag your underbus bag with name, phone, and destination — Megabus does not provide tags.
- Expect one 20-to-30-minute meal stop at a service plaza partway through the trip.
Booking
Tickets for the Canton–Des Moines route are sold only on the official Megabus website and the Megabus app. RouteRider does not sell tickets; we link directly to the operator booking page so you always pay the carrier price with no markup.